Peptide Compass · Research
Kisspeptin-10: research, prices and suppliers
The shortest bioactive fragment of the body's own kisspeptin system, studied in endocrine research on control of the hypothalamic-pituitary-gonadal axis.
Kisspeptin-10 is the shortest fragment of the body's own peptide kisspeptin (metastin) that retains full activity at the KISS1R receptor. In research it is used to trigger GnRH release directly and to study the hypothalamic-pituitary-gonadal axis in questions of pubertal development, hypogonadism, and fertility. Larger clinical trials on endpoints such as oocyte maturation or sexual arousal mostly used the longer natural isoform kisspeptin-54, which acts on the same receptor.
Facts
- CAS number: 374675-21-5
- Molecular weight: 1302.4 g/mol
- Amino acids: 10
- Purity specification: ≥ 98 % (HPLC, commercial standard)
- Solubility: soluble in water and aqueous buffers
Evidence
- In a study in healthy men, an intravenous kisspeptin-10 bolus raised LH levels with increasing effect at higher amounts, and a low-concentration continuous infusion additionally increased LH pulse frequency. George JT et al. 2011, The Journal of Clinical Endocrinology & Metabolism, PMID 21632807
- In a randomized trial in 60 women at high risk of OHSS, a single injection of the related isoform kisspeptin-54 triggered oocyte maturation in 95 percent of cases during an IVF cycle, with no moderate to severe OHSS observed. Jayasena CN et al. 2015, The Journal of Clinical Endocrinology & Metabolism, PMID 26192876
- In a randomized, placebo-controlled trial in 32 men with hypoactive sexual desire disorder, a single infusion of the isoform kisspeptin-54 increased sexual brain activity and penile tumescence during erotic video viewing compared with placebo. Mills EG et al. 2023, JAMA Network Open, PMID 36735255
Frequently asked questions
Is kisspeptin-10 the same as the kisspeptin tested in clinical trials
Not quite. Most major clinical trials on fertility or sexual arousal used the longer natural isoform kisspeptin-54. Kisspeptin-10 is the shortest fragment with full receptor activity and has mainly been studied in mechanistic research on LH release in men.
How does kisspeptin-10 act on the body
It binds to the KISS1R receptor on GnRH neurons in the hypothalamus and triggers pulsatile GnRH release. This downstream governs LH and FSH secretion from the pituitary gland and, with it, central functions of the reproductive axis.
Is kisspeptin-10 legally available in Germany
Kisspeptin-10 is not approved as a medication in Germany, the EU, or the United States. It is offered exclusively as a research chemical for laboratory purposes, not for human use.
Documented prices
Prices are recorded snapshots. Each entry states its date, currency and pack variant. Shipping, tax treatment, discount conditions and availability must be rechecked in the shop. A low price is not evidence of quality.
List prices excluding shipping and discounts. Currency and product variants must be compared separately. Availability and delivered batch have not been verified.
| Vendor | Pack | List price | Price/mg | Recorded | Source |
|---|---|---|---|---|---|
| Peak Peptide | 5 mg | 29.99 EUR | 6.0 EUR/mg | 2026-09-15 | Product page · Ad |
| Europa-Peptide | 5 mg | 38.9 EUR | 7.78 EUR/mg | 2026-09-15 | Product page · Ad |
| Peptide Shop Deutschland | 10 mg | 34.99 EUR | 3.5 EUR/mg | 2026-09-15 | Product page · Ad |
| Bio BoostX | 10 mg | 49.95 EUR | 5.0 EUR/mg | 2026-09-15 | Product page · Ad |
| Peptidwerk | 10 mg | 49.95 EUR | 5.0 EUR/mg | 2026-09-15 | Product page · Ad |
| Beyond Peptides | 10 mg | 50.35 EUR | 5.04 EUR/mg | 2026-09-15 | Product page · Ad |
| Peak Peptide | 10 mg | 54.99 EUR | 5.5 EUR/mg | 2026-09-15 | Product page · Ad |
| Peptide Shop Deutschland | 10 mg | 58 EUR | 5.8 EUR/mg | 2026-09-15 | Product page · Ad |
| Peptide Labz | 10 mg | 95 EUR | 9.5 EUR/mg | 2026-09-15 | Product page · Ad |
| DN Lab Research | 15 mg | 165 EUR | 11.0 EUR/mg | 2026-09-15 | Product page · Ad |
| Licensed Peptides | 5 mg | 68.99 USD | 13.8 USD/mg | 2026-09-15 | Product page · Ad |
| Chameleon Peptides | 10 mg | 42 USD | 4.2 USD/mg | 2026-09-15 | Product page · Ad |
| American Peptides | 10 mg | 60 USD | 6.0 USD/mg | 2026-09-15 | Product page · Ad |
| Protide Health | 10 mg | 75 USD | 7.5 USD/mg | 2026-09-15 | Product page · Ad |
Questions about interpretation
What does the search “Kisspeptin-10 protocol” mean?
“Protocol” is often used to mean a regimen. This page explains research and documented listings. It contains no doses, cycles or instructions for human use. An online regimen is not scientifically validated simply because it is widely shared.
Sources and data basis
These references come from the existing dataset. A link alone verifies neither a study claim nor supplier quality. Uncertainty remains explicit where records are undated or incomplete.
Where to go next
Created with AI assistance. This new edition has not yet received independent editorial review.