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Peptide Compass · Research

KPV: research, prices and suppliers

A three-amino-acid fragment of alpha-MSH, studied in animal models for anti-inflammatory properties in the gut and on the skin.

Sources and dates are stated with individual entries. This new presentation is not a complete re-investigation of all data.

KPV is a tripeptide made of the amino acids lysine, proline, and valine, derived from the C-terminal end of the hormone alpha-MSH. It is among the smallest peptides studied in inflammation research, with a focus on animal models of chronic inflammatory bowel disease and skin inflammation. Human studies are not yet available.

Facts

  • CAS number: 67727-97-3
  • Molecular weight: 342.43 g/mol
  • Amino acids: 3

Evidence

  • A study in two mouse models of colitis described faster body-weight recovery and markedly reduced inflammatory infiltrates in the intestinal tissue under KPV compared with untreated animals. Kannengiesser et al. 2008, Inflammatory Bowel Diseases, PMID 18092346
  • A study showed that the anti-inflammatory effect of KPV in the mouse model is mediated through uptake via the peptide transporter PepT1 rather than the melanocortin receptor. Dalmasso et al. 2008, Gastroenterology, PMID 18061177
  • A study using hyaluronic-acid-functionalized nanoparticles for targeted oral colon release of KPV described significant reduction of inflammation in mice with colitis compared with untreated KPV. Xiao et al. 2017, Molecular Therapy, PMID 28143741

Frequently asked questions

Where does KPV come from?


KPV is a fragment of the hormone alpha-MSH, made of the three amino acids lysine, proline, and valine.

Does KPV act through the melanocortin receptor?


No. In animal models, the anti-inflammatory effect is described independently of the melanocortin receptor, instead relying on the transporter PepT1.

Are there human studies on KPV?


No, to date only cell and animal studies exist, mostly on inflammatory bowel disease.

Documented prices

Prices are recorded snapshots. Each entry states its date, currency and pack variant. Shipping, tax treatment, discount conditions and availability must be rechecked in the shop. A low price is not evidence of quality.

List prices excluding shipping and discounts. Currency and product variants must be compared separately. Availability and delivered batch have not been verified.

VendorPackList pricePrice/mgRecordedSource
Particle Peptides5 mg33.99 EUR6.8 EUR/mg2026-09-15Product page · Ad
Smart Peptides10 mg34.9 EUR3.49 EUR/mg2026-09-15Product page · Ad
Peak Peptide10 mg39.9 EUR3.99 EUR/mg2026-09-15Product page · Ad
Peptide Shop Deutschland10 mg44.98 EUR4.5 EUR/mg2026-09-15Product page · Ad
Peptidwerk10 mg49.95 EUR5.0 EUR/mg2026-09-15Product page · Ad
Beyond Peptides10 mg51.94 EUR5.19 EUR/mg2026-09-15Product page · Ad
Bio BoostX10 mg55.95 EUR5.6 EUR/mg2026-09-15Product page · Ad
Europa-Peptide10 mg62.9 EUR6.29 EUR/mg2026-09-15Product page · Ad
Peptide Labz10 mg75 EUR7.5 EUR/mg2026-09-15Product page · Ad
DN Lab Research15 mg145 EUR9.67 EUR/mg2026-09-15Product page · Ad
Chameleon Peptides5 mg36.9 USD7.38 USD/mg2026-09-15Product page · Ad
Chameleon Peptides10 mg57.6 USD5.76 USD/mg2026-09-15Product page · Ad
American Peptides10 mg60 USD6.0 USD/mg2026-09-15Product page · Ad
Protide Health10 mg70 USD7.0 USD/mg2026-09-15Product page · Ad
Licensed Peptides10 mg76.99 USD7.7 USD/mg2026-09-15Product page · Ad

Questions about interpretation

What does the search “KPV protocol” mean?

“Protocol” is often used to mean a regimen. This page explains research and documented listings. It contains no doses, cycles or instructions for human use. An online regimen is not scientifically validated simply because it is widely shared.

Sources and data basis

These references come from the existing dataset. A link alone verifies neither a study claim nor supplier quality. Uncertainty remains explicit where records are undated or incomplete.

Where to go next

Created with AI assistance. This new edition has not yet received independent editorial review.