Peptide Compass · Research
IGF-1 LR3: research, prices and suppliers
A genetically lengthened analogue of IGF-1 with 83 amino acids, studied in animal models for growth effects and listed as a doping substance in competitive sport.
IGF-1 LR3 is a recombinant analogue of the naturally occurring insulin-like growth factor 1, originally developed for cell-culture research. It carries additional amino acids at the N-terminus and an altered position 3, which makes it largely unable to bind IGF-binding proteins. It is studied mainly in animal models of organ and cell growth, but outside research it is also widely used for purported performance enhancement without solid human data.
Facts
- Molecular weight: 9111.4 g/mol
- Amino acids: 83
- Purity specification: ≥ 98 % (HPLC, commercial standard)
Evidence
- An infusion study in guinea pigs described increased organ growth under long R3 IGF-1, while at the same time plasma levels of endogenous IGF-1, IGF-2, and IGF-binding proteins declined. Conlon et al. 1995, Journal of Endocrinology, PMID 7561636
- A cell study in fetal sheep cardiomyocytes used IGF-1 LR3 as a stable receptor stimulus and described cell proliferation mediated through the ERK and PI3K pathways. Sundgren et al. 2003, American Journal of Physiology, PMID 12947030
- A 2026 review described a substantial gap between the clinical evidence base for growth-hormone-axis peptides such as IGF-1 LR3 and their widespread self-administration outside medical supervision. Dominikowski et al. 2026, Frontiers in Endocrinology, PMID 42395176
Frequently asked questions
What distinguishes IGF-1 LR3 from natural IGF-1?
IGF-1 LR3 carries additional amino acids at the N-terminus and an altered position 3, which means it barely binds IGF-binding proteins and therefore acts on the receptor longer and more strongly than native IGF-1.
Is IGF-1 LR3 allowed in sport?
No, it is listed as a growth factor on the WADA Prohibited List (category S2) and is banned at all times in organized sport.
Are there human studies on IGF-1 LR3?
Controlled human studies are not available, the existing evidence comes from cell and animal models, a 2026 review points to this evidence gap.
Documented prices
Prices are recorded snapshots. Each entry states its date, currency and pack variant. Shipping, tax treatment, discount conditions and availability must be rechecked in the shop. A low price is not evidence of quality.
List prices excluding shipping and discounts. Currency and product variants must be compared separately. Availability and delivered batch have not been verified.
| Vendor | Pack | List price | Price/mg | Recorded | Source |
|---|---|---|---|---|---|
| Driada | 1 mg | 59 EUR | 59.0 EUR/mg | 2026-09-15 | Product page · Ad |
| Europa-Peptide | 1 mg | 62.9 EUR | 62.9 EUR/mg | 2026-09-15 | Product page · Ad |
| Peptide Labz | 1 mg | 75 EUR | 75.0 EUR/mg | 2026-09-15 | Product page · Ad |
| Bio BoostX | 1 mg | 79.95 EUR | 79.95 EUR/mg | 2026-09-15 | Product page · Ad |
| Beyond Peptides | 1 mg | 95.22 EUR | 95.22 EUR/mg | 2026-09-15 | Product page · Ad |
| Peptide Shop Deutschland | 1 mg | 99.99 EUR | 99.99 EUR/mg | 2026-09-15 | Product page · Ad |
| DN Lab Research | 1 mg | 249 EUR | 249.0 EUR/mg | 2026-09-15 | Product page · Ad |
| Chameleon Peptides | 1 mg | 79.2 USD | 79.2 USD/mg | 2026-09-15 | Product page · Ad |
| American Peptides | 1 mg | 85 USD | 85.0 USD/mg | 2026-09-15 | Product page · Ad |
| Protide Health | 1 mg | 85 USD | 85.0 USD/mg | 2026-09-15 | Product page · Ad |
| Licensed Peptides | 1 mg | 124.99 USD | 124.99 USD/mg | 2026-09-15 | Product page · Ad |
Questions about interpretation
What does the search “IGF-1 LR3 protocol” mean?
“Protocol” is often used to mean a regimen. This page explains research and documented listings. It contains no doses, cycles or instructions for human use. An online regimen is not scientifically validated simply because it is widely shared.
Sources and data basis
These references come from the existing dataset. A link alone verifies neither a study claim nor supplier quality. Uncertainty remains explicit where records are undated or incomplete.
Where to go next
Created with AI assistance. This new edition has not yet received independent editorial review.